The ability to diagnose autoimmune thyroiditis with an X-ray fluorescence method to determine the level of stable intrathyroid iodine
https://doi.org/10.14341/probl11766
Abstract
The concentration of intrathyroid stable iodine (ISI) is measured using a Russian commercial reference specimen for noninvasive x-ray fluorescent analysis in 74 women with autoimmune thyroiditis (verified cytomorphologically) aged 36-55 years, residents of Moscow, and in 36 women without a history of thyroid diseases, with normal thyroid status confirmed by clinical and laboratory data and /SI level of at least 200 pg/g, which is considered as the critical (control). Noninvasive x-ray fluorescent method for detecting ISI deficiency permits the recognition of autoimmune thyroiditis with sensitivity and accuracy of at least 9% but with low specificity, which recommends it for screening diagnosis.
About the Author
I. O. TomashevskyClinical Hospital of the Central Health Unit No. 119 of the Federal Administration for Biomedical and Extreme Problems under the Ministry of Health of the Russian Federation
Russian Federation
References
1. Бронштейн М. Э. // Пробл. эндокринол. — 1991. — № 2. — С. 6-10.
2. Бронштейн М. Э. // Там же. — 1997. — № 3. — С. 30—38.
3. Кандрор В. И., Крюкова И. В., Крайнова С. И. и др. // Там же. — С. 25—30.
4. Томашевский И. О. // Там же. — 1996. — № 3. — С. 29—32.
5. Шилин Д. Е., Касаткина Э. П., Пыков М. И. и др. // Актуальные проблемы эндокринологии: Тезисы докладов 3-го Всероссийского съезда эндокринологов. — М., 1996. — С. 173.
6. Alos N., Huot С., Lambert R. et al. // J. Pediatr. — 1995. — Vol. 127, N 6. P. 951-953.
7. Centani J. // Thyroid International / Eds G. Hennemann, E. Krennin. 1995. N 5/6. P. 5.
8. Drexhage H. A. // Thyroid International / Eds G. Hennemann, E. Krennin. — 1994. — N 4. — P. 3—15.
9. Drexhage H. A. // Thyriod International / Eds G. Hennemann, E. Krennin. — 1995. — N 5/6. — P. 5.
10. Hoffer P. B., Bernastein J., Gottschalk A. // Semin. Nucl. Med. — 1971. Vol. 1, N 3. P. 379-389.
11. Huan D. // Thyroid International / Eds G. Hennemann, E. Krennin. 1995. N 5/6. P. 5.
12. Imanishi Y., Ehara N., Mori J. et al. // J. Comput. Assist. Tomogr. 1991. Vol. 15, N 2. P. 287-290.
13. Jonckheer M. H., Vanhaelst L., Deconinck F. et al. // J. clin. Endocrinol. Metab. — 1981. — Vol. 53, N 3. — P. 476—479.
14. Kasagi 1. // Thyriod International / Eds G. Hennemann, E. Krennin. — 1995. — N 5/6. — P. 4.
15. Kobe I. // Ibid. P. 4.
16. Lazarus J. H. // Thyroid International / Eds G. Hennemann, E. Krennin. 1996. N 5. P. 3-12.
17. Mann K., Sailer B., Hoermann R. // Thyroid International / Eds G. Hennemann, E. Krennin. — 1997. — N 2. — P. 8.
18. Tunbridge M. Ц Ibid. N 4. P. 27.
19. X-ray Fluorescent Scanning of the Thyroid / Eds M. H. Jonckheer, F. Deconinck. — Boston, 1983.
20. Zubaschev /. // Thyroid International / Eds G. Hennemann, E. Krennin 1995. N 5/6. P. 3.
Review
For citations:
Tomashevsky I.O. The ability to diagnose autoimmune thyroiditis with an X-ray fluorescence method to determine the level of stable intrathyroid iodine. Problems of Endocrinology. 1999;45(3):28-30. (In Russ.) https://doi.org/10.14341/probl11766

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