Correction of pseudoresistance to sulfonylureas with amaryl
https://doi.org/10.14341/probl11859
Abstract
Pseudoresistance to sulfonylurea drugs is caused by their chronic overdosage and the resultant hypoglycemic reactions leading to decompensation of diabetes. The efficiency of amaril was studied in patients with type 2 diabetes ineffectively treated by traditional sulfonylurea. Amaril therapy in this group of patients resulted in a decrease of glycated hemoglobin fraction A/c by 2.2% in 3 months. Side effects were rare. Hence, amaril can be regarded as a drug for correcting pseudoresistance to sugar-reducing sulfonylurea drugs in patients with type 2 diabetes, as it notably improves carbohydrate metabolism.
About the Authors
A. V. DrevalMoscow Regional Clinical Research Institute named after M.F. Vladimirsky
Russian Federation
I. V. Misnikova
Moscow Regional Clinical Research Institute named after M.F. Vladimirsky
Russian Federation
References
1. Draeger Е. // Diabet. Res. Clin. Pract. — 1995. — Vol. 28. — Suppl. P. S139-SI46.
2. Tsumura K. // Ibid. P. S147—S149.
Review
For citations:
Dreval A.V., Misnikova I.V. Correction of pseudoresistance to sulfonylureas with amaryl. Problems of Endocrinology. 2000;46(4):17-18. (In Russ.) https://doi.org/10.14341/probl11859
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