Activation of the sympathetic-adrenal system by the administration of corticoliberin in the caudate nucleus of dogs
https://doi.org/10.14341/probl11951
Abstract
Corticotrophin releasing factor injection into the head of the caudate nucleus of dogs was followed by a more than threefold increase of blood plasma adrenaline and noradrenaline levels as soon as in 30 min and . by their reduction by the 60th min after the injection though not to the initial values. These changes are compatible to stressor reaction and are associated with an increased orientation research reaction in animals. Injections of 6-hydroxydopamine into caudate nucleus drastically exhausted dopamine content in this structure. Subsequent injections of corticotrophin releasing factor into caudate nucleus virtually did not change blood plasma catecholamine content, this indicating the participation of the strionigral complex dopaminergic structures in realization of corticotrophin releasing factor effect on the sympathoadrenal system.
About the Authors
V. V. RakitskayaPavlov Institute of Physiology RAS
Russian Federation
V. G. Shalyapina
Pavlov Institute of Physiology RAS
Russian Federation
N. L. Voilokova
Pavlov Institute of Physiology RAS
Russian Federation
N. F. Suvorov
Pavlov Institute of Physiology RAS
Russian Federation
E. V. Turkina
Pavlov Institute of Physiology RAS
Russian Federation
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Review
For citations:
Rakitskaya V.V., Shalyapina V.G., Voilokova N.L., Suvorov N.F., Turkina E.V. Activation of the sympathetic-adrenal system by the administration of corticoliberin in the caudate nucleus of dogs. Problems of Endocrinology. 1993;39(6):50-52. (In Russ.) https://doi.org/10.14341/probl11951
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