Therapy of the climacteric disorders in women with type II diabetes
https://doi.org/10.14341/probl12083
Abstract
The efficacy of estrogen-gestagen therapy of patients with climacteric syndrome is no longer doubted. Besides reducing the number of hot flashes, hyperhidrosis, etc., such treatment prevents atherosclerosis, osteoporosis, and atrophy of the external genitals. However, hormone replacement therapy of diabetics with climacteric syndrome involves a high risk of deteriorating carbohydrate metabolism. This study was aimed at elucidating the possibility of using Divine (Orion, Finland) for the treatment of patients suffering from climacteric syndrome in the presence of type II diabetes concomitant with coronary heart disease. The results indicate that the divine had a favorable impact on the course of the climacteric syndrome in the named patient population, appreciably improving the patient's quality of life and causing no decompensation of diabetes, which was confirmed by clinical and laboratory findings.
About the Authors
S. A. PopkovRussian Federation
N. T. Starkova
Russian Federation
T. P. Morozova
Russian Federation
Yu. V. Volobuyeva
Russian Federation
References
1. Мануйлова И. А. Современные контрацептивные средства. - М., 1993. - С. 195.
2. Godsland J., Crook D., Simpson R. et al. // N. Engl. J. Med. — 1990. - Vol. 323. - P. 1375-1381.
3. Godsland J., Walton C., Stevenson J. // Cardiovascular Disease and EIRT. New Perspectives. — New York, 1993. — P. 15— 21.
4. Grady D., Rubin C., Pettiti D. et al. // Ann. intern. Med. — 1992. - Vol. 117. - P. 1016-1037.
5. Gruchow H. W., Anderson A. J., Barborlak J. J., Sobocinski M. S. // Amer. Heart J. - 1988. - Vol. 115. - P. 954-963.
6. Hunter M. S. // Maturitas. — 1990. — Vol. 12. — P. 299—314.
7. Limouzin-Lamothe M.-A., Matron N., Joyce C. R. B. // Amer. J. Obstetr. Gynecol. — 1994. — Vol. 170. — P. 618—624.
8. Marsh C., Crock D., Whitoroft S. et al. // Obstetr. Gynecol. — 1994. - Vol. 83. - P. 19-23.
9. Nabulsi A. A., Folsom A. R., White A. et al. // N. Engl. J. Med. - 1993. - Vol. 328. - P. 1069-1075.
10. Seed M., Crook D. // Curr. Opin. Lipidol. — 1994. — Vol. 5. - P. 48-58.
11. Sherwin В. B. // Ann. N. Y. Acad. Sci. — 1994. — Vol. 743. — P. 213—231.
12. Stampfer M., Colditz G., Willet W. et al. // N. Engl. J. Med. — 1991. - Vol. 325. - P. 756-762.
13. Stampfer M., Colditz G. // Prev. Med. — 1991. — Vol. 20. — P. 47-63.
14. Fan den Brink H. R., van Everdingen A. A., van Wijk M. J. G. et al. // Ann. Rheum. Dis. — 1993. — Vol. 52. — P. 862— 865.
Review
For citations:
Popkov S.A., Starkova N.T., Morozova T.P., Volobuyeva Yu.V. Therapy of the climacteric disorders in women with type II diabetes. Problems of Endocrinology. 1996;42(5):18-20. (In Russ.) https://doi.org/10.14341/probl12083

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