Use of laser doppler flowmeter for the early diagnosis of diabetic microangiopathies

Abstract

Use of laser doppler flowmeter helped reveal in patients with diabetes mellitus a decrease of volumetric bloodstream in the capillaries of skin in the absence of clinical and biochemical evidence of microcirculatory disorders. Bloodstream parameters were correlated to the findings of objective methods of diagnosis at the stage of manifest clinical signs of vascular involvement of various localizations. Laser doppler flowmeter may be used for preclinical diagnosis of renal and ophthalmic involvement in diabetics with types 1 and II conditions as a method to monitor the therapy efficacy in patients with apparent clinical signs of microangiopathies. We should like to emphasize the possibility of mass screenings of patients and the simple technique of using the device, as well as the possibility of assessing the bloodstream not only in the skin, but in the organs and retina as well.