Problems of Endocrinology

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ISSN 2308-1430 (Online)

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ACTH ectopic syndrome caused by corticomedullary mixed tumor

Evgeniya Ivanovna Marova, Nikolay Sergeevich Kuznetsov, Lyudmila Yakovlevna Rozhinskaya, Oleg Valer'evich Remizov, Nonna Vadimovna Latkina, Ol'ga Vladimirovna Tikhonova, Lyubov Efimovna Kats, Iya Aleksandrovna Voronkova, Anastasiya Mikhaylovna Lapshina, Galina Sergeevna Kolesnikova

https://doi.org/10.14341/probl201662150-54

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Abstract

We report the case of a 61 year old woman with a typical clinical picture of ACTH dependent Cushing’s syndrome. Diagnostic tests confirmed ACTH dependent Cushing’s syndrome, which is caused by corticomedullary mixed tumor. ACTH-secreting pheochromocytoma are rarely described in accessible literature, there is no one case report about ACTH-secreting corticomedullary mixed tumor. Due to the rarity of the disease, we believe it appropriate to share our experience and consider all variants of interaction in hypothalamic-pituitary-adrenal axis, which could lead to morphology and clinical changes uncovered in this case.

Keywords

ACTH dependent Cushing’s syndrome, Cushing’s disease, pheochromocytoma, neuroendocrine tumor, corticomedullary mixed tumor

About the Authors

Evgeniya Ivanovna Marova

Endocrinology Research Centre
Russian Federation
MD, PhD, Professor

Nikolay Sergeevich Kuznetsov

Endocrinology Research Centre
Russian Federation
MD, PhD, Professor

Lyudmila Yakovlevna Rozhinskaya

Endocrinology Research Centre
Russian Federation
MD, PhD, Professor

Oleg Valer'evich Remizov

Endocrinology Research Centre
Russian Federation
MD, PhD

Nonna Vadimovna Latkina

Endocrinology Research Centre
Russian Federation
MD, PhD

Ol'ga Vladimirovna Tikhonova

Endocrinology Research Centre
Russian Federation
MD, PhD-student

Lyubov Efimovna Kats

Endocrinology Research Centre
Russian Federation
MD, PhD

Iya Aleksandrovna Voronkova

Endocrinology Research Centre
Russian Federation
MD, PhD

Anastasiya Mikhaylovna Lapshina

Endocrinology Research Centre
Russian Federation
MD, PhD

Galina Sergeevna Kolesnikova

Endocrinology Research Centre
Russian Federation
PhD

References

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Supplementary files

	1. МСКТ брюшной полости и забрюшинного пространства
	Subject
	Type	Исследовательские инструменты
	View (61KB)	Indexing metadata ▾

	2. Смешанно-клеточное строение
	Subject
	Type	Исследовательские инструменты
	View (1MB)	Indexing metadata ▾

	3. ИГХ смешанно-клеточной опухоли (антитела к АКТГ)
	Subject
	Type	Исследовательские инструменты
	View (1MB)	Indexing metadata ▾

Review

For citations:

Marova E.I., Kuznetsov N.S., Rozhinskaya L.Ya., Remizov O.V., Latkina N.V., Tikhonova O.V., Kats L.E., Voronkova I.A., Lapshina A.M., Kolesnikova G.S. ACTH ectopic syndrome caused by corticomedullary mixed tumor. Problems of Endocrinology. 2016;62(1):50-54. https://doi.org/10.14341/probl201662150-54

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ISSN 0375-9660 (Print)
ISSN 2308-1430 (Online)