Pregnancy in acromegaly: a new clinical case and brief reviuw of the liturature
https://doi.org/10.14341/probl201359672-76
Abstract
Women of reproductive age with acromegaly can be interested in pregnancy, even when the pituitary tumor keeps rather big sizes, or control over secretion of GH and IGF-1 has not been reached. In this regard doctors often meet questions of acromegaly influence on the course of pregnancy. Now a little more than 100 cases of pregnancy at acromegalic female patients were described. In article the short review of the cases published in literature is carried out, and a new own clinical case of pregnancy at the patient with acromegaly is represented. The young woman (24 y.o.) received treatment with octreotide prolonged release in a dose 20/40 mg after non-radical adenomectomy for somatoprolactinoma, on this background she became pregnant, and continued medical treatment during all pregnancy. There were no complications during pregnancy and/or pathology of fetal formation. In women with acromegaly treatment with somatostatin analogs is not the indication for pregnancy interruption. It is possible to stop this treatment for the period of pregnancy as such break in treatment is safe for mother and fetus in most cases according to the literature. However if the estimated risk of further growth of a pituitary tumor is high, treatment can be continued during pregnancy.
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Review
For citations:
Ilovaĭskaia I.A., Dreval' A.V., Pokramovich I.G. Pregnancy in acromegaly: a new clinical case and brief reviuw of the liturature. Problems of Endocrinology. 2013;59(6):72-76. (In Russ.) https://doi.org/10.14341/probl201359672-76
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