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Проблемы Эндокринологии

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Конфокальная микроскопия роговицы - новый неинвазивный метод диагностики начальных проявлений повреждения периферической нервной системы при сахарном диабете

https://doi.org/10.14341/probl201561232-38

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Аннотация

В настоящее время не существует надежных способов диагностики начальных проявлений повреждения периферической нервной системы. Только пункционная биопсия кожи и биопсия нервов могут быть использованы на доклинической стадии, однако эти методы инвазивны и сопряжены с риском инфекционных осложнений. Конфокальная микроскопия роговицы - новый неинвазивный морфометрический метод, позволяющий выявлять признаки раннего повреждения периферической нервной системы и исследовать динамику изменений, что может служить суррогатной точкой для оценки терапевтической эффективности лекарственных препаратов.

Об авторах

Е В Артемова
ФГБУ «Эндокринологический научный центр» Минздрава России, Москва


Г Р Галстян
ФГБУ «Эндокринологический научный центр» Минздрава России, Москва


Д С Атарщиков
ФГБУ «Эндокринологический научный центр» Минздрава России, Москва


А А Мальчугина
ФГБУ «Эндокринологический научный центр» Минздрава России, Москва


И И Дедов
ФГБУ «Эндокринологический научный центр» Минздрава России, Москва


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Для цитирования:


Артемова Е.В., Галстян Г.Р., Атарщиков Д.С., Мальчугина А.А., Дедов И.И. Конфокальная микроскопия роговицы - новый неинвазивный метод диагностики начальных проявлений повреждения периферической нервной системы при сахарном диабете. Проблемы Эндокринологии. 2015;61(2):32-38. https://doi.org/10.14341/probl201561232-38

For citation:


Artemova E.V., Galstyan G.R., Atarshchikov D.S., Malchugina A.A., Dedov I.I. Confocal retinal microscopy - the new non-invasive method for diagnostics of the early manifestations of the lesions in the peripheral nervous system associated with diabetes mellitus. Problems of Endocrinology. 2015;61(2):32-38. (In Russ.) https://doi.org/10.14341/probl201561232-38

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