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Primary hyperparathyroidism: the clinical picture, diagnostics, differential diagnostics, and methods of treatment

Abstract

Primary hyperparathyroidism (PHT) is the third most common endocrine disorder in men and women after diabetes mellitus and thyroid disease and one of the most frequent causes of osteoporosis and fractures among the secondary osteopathy. PHT refers to socially significant problems in connection with involvement in the pathological process of the majority of organs and system In recent years, the conception of epidemiology, clinic and tactics of management of patients with PHT has changed due to significant increase of morbidity at the expense of identification of mild forms of disease. The modern management concept tactics depends on clinical manifestations. Bearing in mind the importance of the problem under consideration, the working group was set up for the development of federal recommendations on the treatment of PHT based on the principles of evidence-based medicine. The experience accumulated by the domestic and international experts was summarized in the federal clinical guidelines on PHT.

About the Authors

Ivan I. Dedov
Endocrinology Research Centre, Moscow
Russian Federation
MD, PhD, Professor


Galina A. Melnichenko
Endocrinology Research Centre, Moscow
Russian Federation
MD, PhD, Professor


Natalia G. Mokrysheva
Endocrinology Research Centre, Moscow
Russian Federation
MD, PhD


Liudmila Y. Rozhinskaya
Endocrinology Research Centre, Moscow
Russian Federation
MD, PhD, Professor


Nikolay S. Kusnezov
Endocrinology Research Centre, Moscow
Russian Federation
MD, PhD


Ekaterina A. Pigarova
Endocrinology Research Centre, Moscow
Russian Federation
MD, PhD


Anna K. Eremkina
Endocrinology Research Centre, Moscow
Russian Federation
MD, PhD


Lilit V. Egshatyan
Endocrinology Research Centre, Moscow
Russian Federation
MD, PhD


Elizaveta O. Mamedova
Endocrinology Research Centre, Moscow
Russian Federation
MD


Julia A. Krupinova
Endocrinology Research Centre, Moscow
Russian Federation
MD


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Dedov I.I., Melnichenko G.A., Mokrysheva N.G., Rozhinskaya L.Y., Kusnezov N.S., Pigarova E.A., Eremkina A.K., Egshatyan L.V., Mamedova E.O., Krupinova J.A. Primary hyperparathyroidism: the clinical picture, diagnostics, differential diagnostics, and methods of treatment. Problems of Endocrinology. 2016;62(6):40-77.

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